Dioxin Body Burden
Dioxins taken-in by living organisms (see Daily Dioxin Intakes) and
absorbed into the body (uptake),
are able to accumulate in the body, resulting in a body
burden, which is the total amount of dioxin uptake
present in the body at any one time.
For dioxins, the body burden is usually expressed in:
-
Mass (weight) Units
I-TEQ
per kilogram of body weight(pg I-TEQ/kg bw )
-
Alternatively, as dioxins accumulate in fat, the body
burden can be expressed in
picogram I-TEQ
per gram of serum lipid, i.e. per
gram of fatty substance in the blood (pg I-TEQ/g
lipid).
Instead of the weight unit picogram (pg), nanogram (ng) can be
used, 1000 pg being 1 ng.
In these units, I-TEQ stands for International Toxicity Equivalent (and is sometimes omitted in writing).More
|
Some Body Burdens at the time ofexposure:
|
|
|
in pg I-TEQ per kg body weight |
in pg I-TEQ per g serum lipid |
See question |
| * Derived by dividing the body burden in
lipids by a factor of 5. |
| ** Derived by multiplying the body burden
per body weight by a factor of 5. |
| Adults in industrialized countries |
2 000 to 6 000 |
10 to 30 ** |
2.1.2 & 7.1.1 |
| Moderatly exposed workers |
3 000 to 13 000 |
15 to 650 ** |
5.1 |
| Highly exposed workers |
28 000 to 400 000 |
140 to 2 400 ** |
2.2.2 & 7.2 |
| SEVESO incident (median values) |
Zone A:
90 000 * Zone B:
25 000 * Max :
10 000 000 *
|
|
2.2.1 |
| US Air Force Ranch hands in Vietnam |
About
10 000
|
About 50 ** |
4.3 |
See also “Estimated tissue concentrations in human
populations exposed to dioxin and dioxin-like compounds"
in Table 2 question 4.3.
Related publication:
Other Figures & Tables on this publication:
Table2. : Estimated tissue concentrations in human
populations exposed to dioxin and dioxin-like compounds
Table 7: Estimated daily dietary intake of PCBs in the USA. a
JECFA ASSESSMENT
Dioxin Body Burden
Toxic Equivalents Scheme (TEFs & TEQs)
Daily Dioxin IntakesSome average daily intakes for long term exposures to dioxins:
Mass (weight) Units
