Yusho(1968)
|
Japan: Ingestion of contaminated rice oil
|
PCBs
PCDFs
PCQs
PCTs
|
|
Adipose tissue wet weight within 1 year of end of
exposure.
2.8 mg/kg PCBs,
5.7 mg 2,3,4,7,8 PeCDF, 1.7µmg Hx total
|
NA
|
600 mg PCBs
3.5 mg PCDFs
(60 kg bw)
|
Yucheng (1979)
|
Taiwan: Ingestion of contaminated rice oil
|
PCBs
PCDFs
PCQs
PCTs
|
|
Lipid adjusted serum within 1 year of end of exposure
60 mg/kg total PCB
(range 4-188)
0.14µ mg/kg PCDF
(range 0-0.27)
|
NA
|
Total ingested dose:
1000 mg PCBs
3.8 mg PCDFs
|
Seveso(1976)
|
TCP reactor release
|
TCDD
|
1976
Zone A: 296
Zone Bmax:80
Zone R: 48
1992
Zone A:6
Zone B*: 52
Zone R: 52
|
1976
Zone A: ND-56,000 (median=450)
Zone B: ND -1450 (median=126)
Zone R: ND-100 (median= 50)
1992
Zone A: 61.5 (mean)
71.5 (median)
Zone B: 16.8 (mean) 12.5 (median)
Zone R: 5.3 (median) 5.5 (median)
|
Zone A:
333.8
388.7
Zone B:
111.4
77.6
|
67
78
22
16
|
Industrial Cohorts
|
|
|
|
|
|
|
NIOSH
|
TCP production
|
TCDD
|
253
|
ND-3300
median: 90mean: 220
|
ND-32,000 median: 2,000
|
ND-6400 median: 400
|
Netherlands
|
|
|
48
|
geom. mean 22.9 (production) 87.2 (accident)
|
geom. Mean286 (17-1160)1434 (301-3683)
|
geom.mean 57 (3-232)287 (60-737)
|
BASF
|
|
|
138
|
15.4 (geom)
84.1(median): 5 yrs after end of experiment
|
approx. 400
|
approx. 80
|
Boehringer -Ingelheim
|
|
|
48
|
48.9 (median):11yrs after end of experiment
|
141 (3-2252)
|
28 (1-450)
|
U.S. Air Force Ranch Hand
|
Aerial spraying of Agent Orange in Vietnam
|
TCDD
|
|
ND-800 median: 12.4
|
approx. 50
|
approx. 10
|
General population
(Germany,
1996)
|
Background
|
PCDD
PCDF
|
139
|
mean: 16.1
median: 15.2
Lowest: 7.3
95% 26.7
|
NA
|
range: 1.5-5 ng (I)TEQ/kg.bw
|