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Managing the potential health risks and protection for workers from occupational exposure to manufactured nanomaterials

 

Glossary over Managing the potential health risks and protection for workers from occupational exposure to manufactured nanomaterials

Carcinogen

A substance, factor or situation that causes or induces cancer. (Source: GreenFacts )

Fine particles

Particulate matter present in air is divided into different categories depending on the size of the particles (aerodynamic diameter).

Fine particles are airborne particles which are smaller than coarse particles. They have an aerodynamic diameter of 2.5 µm or less (PM2.5). The fine particles which are smaller than 0.1 µm are referred to as ultrafine particles (PM0.1).

  • Fine particles are largely formed from gases.
  • Ultrafine particles are formed by nucleation, which is the initial stage in which gas becomes a particle. These particles can grow up to a size of 1µm either through condensation, when additional gas condensates on the particles, or through coagulation, when two or more particles combine to form a larger particle.

Please note that ultrafine particles (PM0.1) are part of the fine fraction (PM2.5). (Source: GreenFacts)

In vitro

In an artificial environment outside a living organism or body. For example, some toxicity testing is done on cell cultures or slices of tissue grown in the laboratory, rather than on a living animal. (Source: ATSDR Glossary of Terms  )

Mutagen

A substance or physical agent that causes mutations, i.e. permanently alters the DNA of a cell. (Source: GreenFacts)

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Nanomaterial

Material with one or more external dimensions, or an internal structure, at nanoscale and which could exhibit novel characteristics compared to the same material at a larger scale. (Source: based on SCENIHR's opinion on the  appropriateness of existing methodologies to assess the potential risks associated with engineered and adventitious products of nanotechnologies )

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Nanometre

Unit of length equal to one millionth of a millimetre (10-9 m). (Source: GreenFacts)

Nanoparticle

Particle with one or more dimensions of the order of about 100 millionth of a millimetre (100 nm) or less.

(Note: In the SCENIHR  opinion on the appropriateness of existing methodologies to assess the potential risks associated with engineered and adventitious products of nanotechnologies, nanoparticles are considered to have two or more dimensions at the nanoscale) (Source: GreenFacts )

Nanoscale

Having one or more dimensions of the order of 100 nm or less. (Source: GreenFacts)

Nanotechnology

Nanotechnology is the science of designing, producing, and using structures and devices having one or more dimensions of about 100 millionth of a millimetre (100 nanometres) or less. (Source: GreenFacts)

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Oxidative stress

The term “oxidative stress” refers to the presence of excessive levels of highly reactive molecules called free radicals in the cell or a lack of molecules called antioxidants that can eliminate those free radicals. (Source: Charles S. Lieber  Alcohol and Hepatitis C )

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Particulate matter

Sum of all microscopic solid and liquid particles, of human and natural origin, that remain suspended in a medium such as air for some time. These particles vary greatly in size, composition, and origin, and may be harmful.

Particulate matter may be in the form of fly ash, soot, dust, fog, fumes etc. (Source: GreenFacts)

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Pigment

A substance that gives colour to tissue. Pigments are responsible for the colour of skin, eyes, and hair. (Source: NCI cancer.gov dictionary  )

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Risk assessment

A scientifically based process consisting of four steps:

  • hazard identification,
  • hazard characterization,
  • exposure assessment and
  • risk characterization
(Source:   Official Journal of the European Communities 2002 L 31 )

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Sensitization

In the context of allergies, sensitization is the process by which a person becomes, over time, increasingly allergic to a substance (sensitiser) through repeated exposure to that substance (Source: GreenFacts)

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Stakeholder

Individuals or groups that are affected by a decision and have an interest in its outcome. (Source: TDM Encyclopedia Glossary   )

Target organ

The biological organ(s) most adversely affected by exposure to a chemical substance. (Source: GreenFacts)

The Joint Group of Experts on the Scientific Aspects of Marine Environmental Protection

The Joint Group of Experts on the Scientific Aspects of Marine Environmental Protection (GESAMP) is an advisory body, established in 1969, that advises the United Nations (UN) system on the scientific aspects of marine environmental protection.

At present GESAMP is jointly sponsored by nine UN organizations with responsibilities relating to the marine environment, and they utilize GESAMP as a mechanism for coordination and collaboration among them. GESAMP functions are to conduct and support marine environmental assessments, to undertake in-depth studies, analyses, and reviews of specific topics, and to identify emerging issues regarding the state of the marine environment. GESAMP itself today consists of 16 experts, drawn from a wide range of relevant disciplines, who act in an independent and individual capacity. Studies and assessments are usually carried out by dedicated working groups, most of whose members are not sitting members of GESAMP but part of the broader GESAMP network.

GESAMP's UN sponsors: IMO, FAO, UNESCO-IOC, WMO, IAEA, UN, UNEP, UNIDO, UNDP.GESAMP

Source: (Source: www.gesamp.org/about  )

Toxicity

The capacity or property of a substance to cause adverse effects. (Source: GreenFacts)

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Toxicology

The study of the harmful effects of substances on humans or animals. (Source: ATSDR Glossary of Terms  )

Virus

A virus is a small organism which can infect other biological organisms.

Viruses can only reproduce by invading and taking over cells as they lack the cellular machinery for self reproduction.

They cause diseases in human beings, animals, plants and bacteria.

Examples of human diseases caused by viruses include the common cold, influenza, small pox, AIDS, and cold sores. (Source: GreenFacts)

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World Health Organization

"The World Health Organization  (WHO) is the directing and coordinating authority on international health within the United Nations’ system. WHO experts produce health guidelines and standards, and help countries to address public health issues. WHO also supports and promotes health research. Through WHO, governments can jointly tackle global health problems and improve people’s well-being.

193 countries and two associate members are WHO’s membership. They meet every year at the World Health Assembly in Geneva to set policy for the Organization, approve the Organization’s budget, and every five years, to appoint the Director-General. Their work is supported by the 34-member Executive Board, which is elected by the Health Assembly. Six regional committees focus on health matters of a regional nature."

WHO's scientific publications are widely recognized as a reference source.

The WHO has a number of regional offices which address the specific issues of those regions.

WHO World Regional Offices
  WHO African Region  (46 countries)
  WHO European Region  (53 countries)
  WHO Eastern Mediterranean Region  (21 countries)
  WHO Region of the Americas  (35 countries)
  WHO South-East Asia Region  (11 countries)
  WHO Western Pacific Region  (27 countries)

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