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Similar term(s): AhR, Aryl hydrocarbon receptor.
Aryl hydrocarbon receptor. A protein within the cell that binds to aryl hydrocarbons forming a complex that moves into the nucleus of the cell. In the nucleus, this complex controls the onset of a series of biotransformation processes for the excretion of hydrocarbon compounds. Ah-receptor binding, may, however also result in the synthesis of other proteins, some of which may interfere adversely with cellular growth and differentiation (specialization).
Source: GreenFacts
Ah receptors are prone to binding with halogenated aromatic hydrocarbons, including dioxins and polychlorinated biphenyls (PCBs), which can cause changes in gene expression, affecting cell growth, form and function. This is the reason these chemicals can be carcinogenic or teratogenic.
Carcinogen - Cell - Dioxin(s) - Enzyme(s) - Molecule - Receptor
Français: Récepteur Ah
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